30 Klebsiella (Carbapenem Resistant)

https://www.cdc.gov/hai/organisms/klebsiella/klebsiella.html

36 cases

16 deaths

47.2 % of cases were hospitalized

3.1 cases per 100,000 population


30.1 Epidemiologic Review

30.1.1 Disease Information

Overview: Carbapenem resistant Klebsiella is a bacterium found in the gastrointestinal tract that is resistant to one or more carbapenem antibiotics. Carbapenemase-producing bacteria make enzymes called carbapenemases that inactivate carbapenems and other β-lactam antibiotics, including penicillins and cephalosporins. The five most common carbapenemases are KPC, NDM, VIM, OXA, and IMP.

Symptoms: Symptoms vary depending on the type of disease and some people may be asymptomatic.

Transmission: Person-to-person contact by infected healthcare personnel or by contaminated medical equipment.

Treatment: Treatment varies with each isolate. Some cases may be susceptible to a small number of antibiotics while others are pan-resistant, meaning no treatment is available.

Prevention Proper hand hygiene, use of personal protective equipment and environmental cleaning practices help reduce the spread of disease. Practicing antibiotic stewardship could help in reducing antibiotic resistance.

30.1.2 Demographics


Racial demographic data are not presented due to low counts.


Ethnicity Rate per 100k
Hispanic or Latino 1.2
Not Hispanic or Latino 3
Unknown <5 cases


Rates for Unknown Ethnicity are not displayed due to low case counts.

30.1.3 Outbreaks

No outbreaks were identified.

30.1.4 Monthly and Historical Comparisons



Data for Utah and the CDC were retrieved from the CDC’s Notifiable Infectious Disease Data Tables and were available up until 2020. National data was not available for this disease in the time range at time of report.

30.2 Key Things to Know

  • 38% of isolates were resistant to 2 or more carbapenems, 12% were resistant to all 4 of the carbapenems.
  • 2 isolates were Carbapenemase producers, both were KPC.
  • 38% of isolates were Klebsiella aerogenes, 14% were Klebsiella oxytoca, 47% were Klebsiella pneumoniae.
  • Common comorbidities among cases included cardiovascular disease, diabetes and obesity.
  • Of the cases who were hospitalized, 67% had a stay in an intensive care unit.